HIV

Stem Cells Can be Engineered into Genetic Vaccines Against HIV and More


While some viruses attack the lungs, and others the blood, HIV attacks the only system that could put up a fight: the immune system itself. The immune system mounts some defense, but after HIV launches its surprise attack, the body simply can't produce enough killer T blood cells to take out the virus.

Now, thanks to researchers at UCLA, it's payback time for the blood cells. A team of scientists have plucked T-cells out of someone infected with HIV, and used them as a template for creating an army of HIV-fighting immune cells out of stem cells. Essentially a genetic vaccine, this technique could be used to copy T-cells designed to fight any virus, opening up the possibility of universal vaccination via stem cell implantation.

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Synthetic Molecules Trick Body Into Improved Immune Response to HIV, Cancer


When it comes to eluding detection, HIV and cancer cells are at the top of the class. As such, the few treatments currently available to sufferers of HIV or prostate cancer are generally expensive, often hard to manufacture, and come packaged with a smattering of unpleasant side effects. But Yale researchers have now developed synthetic molecules that help the body recognize HIV and prostate cancer cells as threats, tricking the body into initiating an immune response that it normally would not.

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Fastest Supercomputer in the World Models Dark Matter, HIV Family Tree Simultaneously

Petaflop power in action

In November of last year, scientists at Los Alamos National Laboratory switched on Roadrunner, the world's fastest computer. IBM and the Department of Energy built the machine to model nuclear explosions, but two new studies, both released today, are proof that the computer's massive power has been at least as devoted to peaceful science as to simulating thermonuclear weapons.

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HIV Vaccine Trial Comes Under Scrutiny


Last month, scientists reported that a clinical trial for an HIV vaccine showed the first-ever success in preventing transmission of the virus. However, a number of HIV researchers believe that the enthusiasm for last month's vaccine results should be dampened in light of a more comprehensive review of the data.

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Link found between brain infection and HIV


A Melbourne-based research team has discovered that infection of a particular type of brain cell is extensive in patients with human immunodeficiency virus (HIV) associated dementia.
The discovery refutes earlier medical studies that suggested HIV infection of astrocyte brain cells was considered rare and that the cells played only a minor role in the development of this disease.

The findings were recently published in the prestigious scientific journal, Annals of Neurology.

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For the First Time Ever, an HIV Vaccine Shows Success in Trial


After over 25 years of failed formulas, an HIV vaccine has, for the first time, displayed the ability to confer some immunity against the virus. Deployed in a clinical trial in Thailand, the vaccine managed to prevent infection in a significant minority of volunteers. However, scientists involved in the study caution that they cannot fully explain the success, and that the vaccine only worked in a portion of those who received it.

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AIDS-Like Virus Threatens Koalas With Extinction


A decade ago, the bells of doom started to sound for carefree, swinging koalas. A new, HIV-like retrovirus had begun to attack the koala population, decimating its ranks and threatening extinction.

Now, the Australian researchers have launched an effort to stop the spread of the virus before it's too late.

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Shape-Shifting Gel Condom Changes From Liquid to Solid To Block HIV


Though the University of Utah in Salt Lake City might not be the first place one would expect to find researchers getting experimental in the bedroom, a team of scientists there have developed a new gel that can quickly shift from liquid to solid, for use in a vaginal condom that more easily protects against both pregnancy and sexually transmitted diseases.

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Researchers Fully Decode HIV Genome For the First Time


Using special techniques developed to sequence RNA, researchers at the University of North Carolina, Chapel Hill, have published the first complete genome of HIV. Laying bare the complete genetic make up of the virus opens up a new era of research, drastically widens the possible experiments that scientists can perform on the virus, and may significantly accelerate our understanding of how HIV infects humans and evades our immune system.

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Tourists May Have Spread HIV

The virus traveled from Mediterranean to colder climes

A new map of the spread of HIV infection in Europe indicates that the virus traveled from major holiday destinations -- Greece, Portugal and Spain -- to northern European countries, New Scientist reports. A virologist determined how the virus evolved by sequencing parts of the virus genome from subjects throughout Europe -- 1,337 people from at least 11 countries. While a number of Mediterranean countries appeared to be sources for the virus, the UK, Netherlands, Italy, Sweden, Norway, Switzerland, Denmark, Germany and Israel appeared to be hubs, through which the virus both came and went.

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HIV Resistance Through Oral Sex?

A new study suggests repeated exposure can help produce resistant antibodies

It has long been known that contracting HIV through oral sex is rare. Klara Hasselrot of Stockholm's Karolinska Institutet recently wrapped up a study--detailed in a forthcoming paper in the international AIDS journal AIDS--that might shed some light on why this is. It provides the first-ever evidence that humans can develop resistance to HIV in their saliva.

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Video Games to Fight AIDS

A new digital project helps Kenyan teens learn healthy behaviors

At CES, where Resident Evil 5 will soon be projected onto the side of Planet Hollywood, video games are everywhere. But some go beyond mere entertainment. During his keynote speech today, Intel chairman Craig Barrett talked about how technology can help people in the developing world. One of the most interesting efforts he mentioned: Warner Brothers Interactive recently created a PC game that uses an engaging story to teach Kenyan teens about HIV prevention.

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A Cure for AIDS

While treating a patient for leukemia, doctors inadvertently cured his case of AIDS

Holy crap. These guys in Germany just cured AIDS!

Of course, the procedure is so expensive, complicated, and risky that it's not replicable as a large-scale public health strategy, but we'll ignore that for a minute. Here's how they did it.

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AIDS Emerged 100 Years Ago, Study Says

New research pushes the emergence of HIV into the 19th Century, points to urbanization of Africa as a cause

One can hardly fathom the horror of life in the Congo Free State during the turn of the last century when native Africans suffered genocide at the hand of Belgium’s King Leopold II. In those conditions, no one would have noticed people dying of a strange disease that would not be named for another hundred years. No one would have noticed people dying of AIDS.

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First Video of a Virus Being Born

Scientists capture the assembly of HIV in action and open the door to a new way to research disease

The video shows what looks like a faint nebula in deep space, its neighboring stars resolving to their full brightness after a long exposure. Only the images are not of the very large and distant; they are exactly the opposite. It is the picture of a cell membrane and the stars are hundreds of thousands of molecules at the cell's surface, gathering together to form a particle of the HIV virus. It is the first video of any virus being born and visually illuminates a process never before documented in real time.

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