Apigenin supplements refer to any dietary supplement that provides apigenin, a plant flavone that’s found in many plants. Apigenin supplements are used to reduce pain and inflammation or help with weight management. The following are 7 of the most studied apigenin supplements benefits. 1. Reduces pain and inflammation Apigenin can help to reduce joint and muscle pain through its anti-inflammatory actions. Apigenin can reduce symptoms of inflammation by inhibiting the COX-2 enzyme, which produces prostaglandins that cause pain and inflammation. Data suggest that apigenin may be as effective at reducing pain as ibuprofen, another common anti-inflammatory drug.  Head to www.apigen.com.au for more information. 2. Helps prevent heart disease Experimental studies suggest that apigenin may be able to help prevent the development of atherosclerosis and heart disease, likely by its anti-inflammatory actions. Animal studies have shown that apigenin can reduce the formation of plaque and cholesterol in arteries. Research also suggests that apigenin may help lower blood pressure and improve blood circulation. Additional research is needed in humans before any firm conclusions can be made about apigenin benefits for cardiovascular health. 3. Helps with weight loss Apigenin has been shown in rat studies to help prevent fat build-up. The study showed that apigenin prevented the accumulation of abdominal fat, which improves insulin resistance and helps protect rats from the development of diabetes. Additional research is needed in humans before any firm conclusions can be made about how effective apigenin is at weight loss. 4. May protect against cancer Apigenin has tumor-suppressing abilities and can stop or slow the growth of cancerous cells. Apigenin can stop the growth of new blood vessels from forming in tumors and cancerous areas, which helps slow the growth of cancerous cells. Despite the promising preliminary studies, additional research is needed in humans before any firm conclusions can be made about apigenin’s benefits for decreasing the risk of various cancers. 5. Helps with digestive problems Most recently, preliminary research shows that apigenin may help with digestive problems like Crohn’s Disease and Irritable Bowel Syndrome. Apigenin may help decrease these conditions by inhibiting certain receptors in the intestines, which can reduce the number of cytokines (signaling proteins) that are released into the intestines. 6. Reduces fatigue, depression, and insomnia Apigenin is available in many forms, including supplements and dietary sources. It is believed to help reduce stress and fatigue, as well as depression. The flavone has also been studied for helping with insomnia. It is thought that apigenin helps with sleep because it affects the brain’s chemical signals that sleep. 7. Increases libido and testosterone In men, the amino acid apigenin has been found to increase testosterone levels by as much as 100%. According to animal studies, this flavone may also increase sexual desire. One study showed that men who took apigenin supplements had a lower sex drive than those who took a placebo. Men taking the supplement, however, showed an increase in their sperm count. Taking apigenin supplements may have a positive effect on your health. There are potential benefits to reducing inflammation, such as reducing pain and risk of heart disease, as well as helping with weight loss. Preliminary studies also show that it may help with digestive problems, fatigue, and depression. Additional research is needed in humans before any firm conclusions can be made about the potential benefits of apigenin.